Two sample MR report
NQO2_Alveolar Macrophages against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.0071971 | 3.3725913 | 0.9986415 |
| Weighted median | 3 | 0.1357955 | 0.0371453 | 0.0002564 |
| Inverse variance weighted | 3 | 0.1355580 | 0.0287896 | 0.0000025 |
| Simple mode | 3 | 0.1361463 | 0.0430129 | 0.0869866 |
| Weighted mode | 3 | 0.1361463 | 0.0416830 | 0.0823264 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0000008 | 1 | 0.9992881 |
| Inverse variance weighted | 0.0017926 | 2 | 0.9991041 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.1010614 | 2.38749 | 0.9730682 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.75e-05 | 0 | TRUE | 0.5693785 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
